{ "affiliate_slug": "probiogen", "also_sold_as": [], "alternatives": [ { "gis": 66.25, "name": "Probiogen Women's Vitality Spore Probiotic", "price": null, "route": "/p/women-s-vitality-spore-probiotic/", "shared_strain": "HU58" }, { "gis": 61.75000000000001, "name": "Probiogen Daily Digestive Balance Probiotic", "price": null, "route": "/p/daily-digestive-balance-probiotic/", "shared_strain": "HU58" }, { "gis": 61.75000000000001, "name": "Probiogen Men's Vitality Spore Probiotic", "price": null, "route": "/p/men-s-vitality-spore-probiotic/", "shared_strain": "HU58" } ], "brand_id": "brand:probiogen", "brand_page": { "name": "Probiogen", "route": "/b/probiogen/" }, "claims": [ { "checked_at": "2026-09-20T00:00:00Z", "claim_id": "claim:p--allergy-defense-probiotic:product.organisms", "denominator": 2, "denominator_status": "ok", "denominator_unit": "observed organisms", "entity_id": "sku:allergy-defense-probiotic", "number": 1, "page_id": "p--allergy-defense-probiotic", "provenance": "organism_rows.csv", "query": "latest observed label organism rows; designation and deposit must be printed", "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0", "query_id": "product.organisms", "query_links": [], "rows_after_dedupe": 1, "rows_before_dedupe": 2, "rule_id": "product.organisms", "sentence": "Probiogen Allergy Defense Probiotic: 1 of 2 observed organisms name a strain, and 0 print a deposit identifier. Latest observed label 255435. Window: NIH DSLD snapshot Sep 2026.", "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "status": "ok", "template_id": "product.organisms", "values_json": "{\"denominator\": 2, \"deposits\": 0, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Probiogen Allergy Defense Probiotic\", \"number\": 1, \"observation_note\": \"Latest observed label 255435.\", \"share\": \"50.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}", "window": "NIH DSLD snapshot Sep 2026" }, { "checked_at": "2026-09-20T00:00:00Z", "claim_id": "claim:p--allergy-defense-probiotic:product.potency", "denominator": 2, "denominator_status": "ok", "denominator_unit": "observed label snapshots", "entity_id": "sku:allergy-defense-probiotic", "number": 0, "page_id": "p--allergy-defense-probiotic", "provenance": "organism_rows.csv; label_versions.csv", "query": "product label snapshots with explicit through_expiry or at_manufacture basis", "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0", "query_id": "product.potency", "query_links": [], "rows_after_dedupe": 0, "rows_before_dedupe": 2, "rule_id": "product.potency", "sentence": "Probiogen Allergy Defense Probiotic: 0 of 2 observed label snapshots state a potency basis; latest basis is not stated. Quantities reflect printed organism rows. Window: NIH DSLD snapshot Sep 2026.", "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "status": "ok", "template_id": "product.potency", "values_json": "{\"basis\": \"not stated\", \"denominator\": 2, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Probiogen Allergy Defense Probiotic\", \"number\": 0, \"quantity_note\": \"Quantities reflect printed organism rows.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}", "window": "NIH DSLD snapshot Sep 2026" }, { "checked_at": "2026-09-20T00:00:00Z", "claim_id": "claim:p--allergy-defense-probiotic:product.gis", "denominator": 1, "denominator_status": "ok", "denominator_unit": "selected label snapshots", "entity_id": "sku:allergy-defense-probiotic", "number": 1, "page_id": "p--allergy-defense-probiotic", "provenance": "composite.csv; cohort_manifest.json", "query": "latest numeric composite availability, GIS, quartile rank_class and normative preference-weight perturbation; no invented rank interval", "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0", "query_id": "product.gis", "query_links": [], "rows_after_dedupe": 1, "rows_before_dedupe": 1, "rule_id": "product.gis", "sentence": "Probiogen Allergy Defense Probiotic: 1 of 1 selected label snapshots have a numeric Gut Index Score; GIS 61.75 on the 100-point scale; rank class 3 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity. Window: NIH DSLD snapshot Sep 2026.", "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "status": "ok", "template_id": "product.gis", "values_json": "{\"denominator\": 1, \"gis\": \"61.75\", \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Probiogen Allergy Defense Probiotic\", \"number\": 1, \"rank_note\": \"rank class 3 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity\", \"scale\": 100.0, \"share\": \"100.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}", "window": "NIH DSLD snapshot Sep 2026" }, { "checked_at": "2026-09-20T00:00:00Z", "claim_id": "claim:p--allergy-defense-probiotic:product.versions", "denominator": 2, "denominator_status": "ok", "denominator_unit": "formulation groups", "entity_id": "sku:allergy-defense-probiotic", "number": 2, "page_id": "p--allergy-defense-probiotic", "provenance": "label_versions.csv; label_version_edges.csv", "query": "observed label versions and distinct formulation IDs; latest typed edge by source_observed_at", "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0", "query_id": "product.versions", "query_links": [], "rows_after_dedupe": 2, "rows_before_dedupe": 2, "rule_id": "product.versions", "sentence": "Probiogen Allergy Defense Probiotic has 2 observed versions across 2 formulation groups; last recorded edge type: available at the same time. Window: NIH DSLD snapshot Sep 2026.", "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "status": "ok", "template_id": "product.versions", "values_json": "{\"denominator\": 2, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"last_change\": \"available at the same time\", \"name\": \"Probiogen Allergy Defense Probiotic\", \"number\": 2, \"share\": \"100.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}", "window": "NIH DSLD snapshot Sep 2026" }, { "checked_at": "2026-09-20T00:00:00Z", "claim_id": "claim:p--allergy-defense-probiotic:product.price", "denominator": 2, "denominator_status": "ok", "denominator_unit": "observed label versions", "entity_id": "sku:allergy-defense-probiotic", "number": 0, "page_id": "p--allergy-defense-probiotic", "provenance": "prices.csv", "query": "numeric price observations joined by latest label_version_id; retain undefined reason", "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0", "query_id": "product.price", "query_links": [], "rows_after_dedupe": 0, "rows_before_dedupe": 2, "rule_id": "product.price", "sentence": "Probiogen Allergy Defense Probiotic: 0 of 2 observed versions have numeric prices; latest price No numeric price observation is available in this release.. Window: NIH DSLD snapshot Sep 2026.", "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "status": "ok", "template_id": "product.price", "values_json": "{\"denominator\": 2, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Probiogen Allergy Defense Probiotic\", \"number\": 0, \"price_text\": \"No numeric price observation is available in this release.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}", "window": "NIH DSLD snapshot Sep 2026" } ], "cohort_manifest_sha256": "3a8805d95e34cbd3ccdc36613e5bbcd4a75c17b7e07e420b65aa54f786a13400", "cohort_wave": "2026-09-20-w2", "compared_with": [], "composite": { "A1": 15, "A1_components_json": "{\"identity\":0.0,\"quantity_disclosure\":0.0,\"potency_basis\":0.0,\"version_traceability\":1.0}", "A2": 100, "cohort_manifest_sha256": "3a8805d95e34cbd3ccdc36613e5bbcd4a75c17b7e07e420b65aa54f786a13400", "components_scored": "A1,A2", "effective_weight_json": "{\"A1\":0.2496227130555789,\"A2\":0.640418048760888}", "evidence_score_basis": "Existing GIS formula applied to known matching records as a lower bound; evidence_status records incomplete query coverage. Unknown evidence counts remain null.", "evidence_status": "ok", "formula_version": "gis_v1", "formulation_id": "formulation:255435", "geometric_sensitivity_interval": "[0.0,0.0]", "gis": 61.75000000000001, "gis_geo": 42.58347183047368, "identity_kind": "species_or_t4", "label_version_id": "255435", "mapping_tier": "T3", "p_top_quartile": 0, "pairwise_order_stability": 0.8460467663209275, "potency_basis": "unstated", "preference_sensitivity_interval": "[0.0,66.42409345068155]", "quantity_disclosure": 0, "rank_class": 3, "rank_median": 2188, "rank_p5": 1973, "rank_p95": 2632.0499999999993, "rank_uncertainty_interval": "[1973.0,2632.0499999999993]", "reason_codes_json": "[\"dose_unknown\",\"identity_t4\"]", "score_status": "scored", "show_exact_rank": false, "sku_id": "sku:allergy-defense-probiotic" }, "eligibility": { "active_gut_ingredients": 0, "eligible": true, "excluded_name_match": false, "label_id": "255435", "organism_rows": 2, "source_kind": "detailed" }, "entity_doses": {}, "entity_id": "sku:allergy-defense-probiotic", "entity_pages": [ { "entity_id": "species:bacillus-clausii", "name": "Bacillus clausii", "route": "/s/bacillus-clausii/" }, { "entity_id": "species:bacillus-subtilis", "name": "Bacillus subtilis", "route": "/s/bacillus-subtilis/" }, { "entity_id": "strain:bacillus-subtilis-hu58", "name": "Bacillus subtilis HU58", "route": "/s/bacillus-subtilis-hu58/" } ], "evidence": { "A2": 100, "above_studied_range": "0", "coverage_definition": "strain_count", "coverage_high": 1, "coverage_low": 0, "coverage_value": 1, "dose_unknown": "1", "evidence_amount": 1, "evidence_entity_ids_json": "[\"species:bacillus-clausii\", \"strain:bacillus-subtilis-hu58\"]", "evidence_queries_json": "[{\"entity_id\": \"species:bacillus-clausii\", \"query\": \"(((\\\"Bacillus clausii\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:bacillus-subtilis-hu58\", \"query\": \"(((\\\"B. subtilis\\\"[tiab] OR \\\"Bacillus subtilis\\\"[tiab]) AND (\\\"HU58\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}]", "evidence_sources_json": "{\"species:bacillus-clausii\": \"v2\", \"strain:bacillus-subtilis-hu58\": \"v2\"}", "known_records_count": 18, "label_version_id": "255435", "match_state": "strain_only", "n_rct_human": 18, "observed_positive_trial_dose_match": "", "query_dates": "2026-09-15", "rct_count": 18, "state": "strain_only", "status": "ok", "unallocated_share": 1, "unmatchable_reason": "dose_unknown" }, "formula_version": "gis_v1", "generated_at": "2026-09-20T00:00:00Z", "label_facts": { "cfu_per_day": null, "days_blocker": "", "days_of_supply": 15, "form": "Capsule", "net": { "display": "120 Vegetarian Capsule(s)", "quantity": 120, "unit": "Vegetarian Capsule(s)" }, "other_ingredient_count": 2, "other_ingredients": [ "HPMC", "Cellulose" ], "price_per_day": null, "printed_claim_count": 2, "printed_claims": [ "All Other", "Structure/Function" ], "product_type": "Other Combinations", "serving": { "per_day": 2, "size": 4, "unit": "Vegetarian Capsule(s)" }, "suggested_use": "Suggested Use: During the loading phase (first 7-10 days) or during times of acute environmental stress, take four (4) capsules twice daily after a meal. For maintenance, take two (2) capsules twice daily after a meal or as directed by your physician.", "target_groups": [ "Adult (18 - 50 Years)", "Gluten Free", "Dairy Free", "Sugar Free" ], "units_comparable": true, "units_converted": false, "upc": "6 89076 07152 9" }, "label_versions": [ { "brand": "Probiogen", "censored": "1", "diff_flags_json": "{}", "effective_from": "", "effective_to": "", "entry_date": "2017-10-21", "label_version_id": "80084", "link_confidence": "", "observation_kind": "detailed", "observed": "1", "observed_at": "2017-10-21", "off_market_date": "", "prev_version_id": "", "product": "Allergy Defense Probiotic", "record_key": "12c8e86c9b98206fb3cd30bfc5300292fc8872093af51cc75bbf3e3f4fc1ade3", "relationships_json": "[]", "sku_id": "sku:allergy-defense-probiotic", "upc": "8 18423 02815 6" }, { "brand": "Probiogen", "censored": "1", "diff_flags_json": "{}", "effective_from": "", "effective_to": "", "entry_date": "2021-09-24", "label_version_id": "255435", "link_confidence": 0.6, "observation_kind": "detailed", "observed": "1", "observed_at": "2021-09-24", "off_market_date": "", "prev_version_id": "80084", "product": "Allergy Defense Probiotic", "record_key": "cd09babac8cc869fb13c603f0fd2dccf73878b2c687390a91398b8469b06c586", "relationships_json": "[]", "sku_id": "sku:allergy-defense-probiotic", "upc": "6 89076 07152 9" } ], "latest_label_id": "255435", "name": "Probiogen Allergy Defense Probiotic", "opinion_type": "observed", "organisms": [ { "blend_total_cfu": "1000000000", "brand": "Probiogen", "canonical_entity_id": "species:bacillus-clausii", "cfu_basis": "unstated", "cfu_basis_row_ref": "", "cfu_per_serving": "", "cfu_scope": "none", "cfu_source": "none", "confidence": "0.60", "culture_collection_id": "", "designation_type": "none", "enumeration_method": "unstated", "extracted_from": "ingredientRows[3].nestedRows[0]", "genus_norm": "Bacillus", "genus_raw": "Bacillus", "in_proprietary_blend": "1", "label_id": "255435", "mapping_tier": "T4", "match_confidence": "0.60", "observation_kind": "detailed", "observed_at": "2021-09-24", "opinion_type": "observed", "parser_version": "w0-v1.1", "product": "Allergy Defense Probiotic", "quantity_unit": "", "quantity_value": null, "raw_name": "Bacillus clausii", "reason_code": "", "record_key": "aa61ac6759ebd3d3cf0cf1cbac370d79572a4b7670dcfb7978b7460d1614f2cc", "retrieved_at": "2026-09-06T10:32:22Z", "source_content_hash": "2f8d9676c094039899d46d3ccc1c2405e622fde3818f63b58831fffe919ab7a6", "source_id": "NIH_DSLD:255435", "source_record_id": "255435", "source_url": "https://dsld.od.nih.gov/label/255435", "species": "clausii", "status": "scored", "strain_designation": "", "taxon_recognized": "1", "viability_state": "unstated" }, { "blend_total_cfu": "1000000000", "brand": "Probiogen", "canonical_entity_id": "strain:bacillus-subtilis-hu58", "cfu_basis": "unstated", "cfu_basis_row_ref": "", "cfu_per_serving": "", "cfu_scope": "none", "cfu_source": "none", "confidence": "0.95", "culture_collection_id": "", "designation_type": "commercial_code", "enumeration_method": "unstated", "extracted_from": "ingredientRows[3].nestedRows[1]", "genus_norm": "Bacillus", "genus_raw": "Bacillus", "in_proprietary_blend": "1", "label_id": "255435", "mapping_tier": "T3", "match_confidence": "0.95", "observation_kind": "detailed", "observed_at": "2021-09-24", "opinion_type": "observed", "parser_version": "w0-v1.1", "product": "Allergy Defense Probiotic", "quantity_unit": "", "quantity_value": null, "raw_name": "Bacillus subtilis HU58", "reason_code": "", "record_key": "8a8b6e73dc76e59d2f1de494e578a19f22ff7a6c7b2cd967e9e65355331365e4", "retrieved_at": "2026-09-06T10:32:22Z", "source_content_hash": "2f8d9676c094039899d46d3ccc1c2405e622fde3818f63b58831fffe919ab7a6", "source_id": "NIH_DSLD:255435", "source_record_id": "255435", "source_url": "https://dsld.od.nih.gov/label/255435", "species": "subtilis", "status": "scored", "strain_designation": "HU58", "taxon_recognized": "1", "viability_state": "unstated" } ], "page_id": "p--allergy-defense-probiotic", "page_type": "product", "panels": [], "price": null, "printed_quantity": { "basis": "unstated", "blend_rows": 2, "rows": 2, "rows_with_quantity": 0, "total_cfu": null, "total_cfu_printed": null, "total_cfu_unreadable": false }, "qualification": "observed", "quantity_note": "Quantities reflect printed organism rows.", "related_reports": [ { "name": "Potency basis census", "route": "/reports/potency-basis-census/" }, { "name": "Strain dose match", "route": "/reports/strain-dose-match/" }, { "name": "Supplier code network", "route": "/reports/supplier-code-network/" } ], "related_tools": [ { "name": "Unit value calculator", "route": "/calc/" }, { "name": "DSLD product check", "route": "/check/" } ], "release": "2026-09-20", "route": "/p/allergy-defense-probiotic/", "score_context": { "percentile": 39.4, "scored_formulations": 4101 }, "score_scale": 100, "source_sha256": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a", "strain_evidence": [ { "entity_id": "species:bacillus-clausii", "evidence_status": "ok", "name": "Bacillus clausii", "query_valid": true, "rct_count": 17, "route": "/s/bacillus-clausii/" }, { "entity_id": "species:bacillus-subtilis", "evidence_status": "ok", "name": "Bacillus subtilis", "query_valid": true, "rct_count": 48, "route": "/s/bacillus-subtilis/" }, { "entity_id": "strain:bacillus-subtilis-hu58", "evidence_status": "ok", "name": "Bacillus subtilis HU58", "query_valid": true, "rct_count": 1, "route": "/s/bacillus-subtilis-hu58/" } ], "version_edges": [ { "changed_fields_json": "{}", "claimed_effective_at": "", "confidence": 0.6, "delta": { "basis_after": "unstated", "basis_before": "unstated", "basis_changed": false, "cfu_after": null, "cfu_before": null, "cfu_changed": false, "comparable": true, "organisms_added": [], "organisms_added_count": 0, "organisms_removed": [], "organisms_removed_count": 0, "pack_after": "120 Vegetarian Capsule(s)", "pack_before": "120 Vegetarian Capsule(s)" }, "edge_type": "coavailable", "entity_changes": {}, "from_label_version_id": "80084", "interval_censored": "1", "relationship_type": "derived_from_observation_windows", "source_observed_at": "2021-09-24", "to_label_version_id": "255435", "window_end": "", "window_start": "2017-10-21" }, { "changed_fields_json": "{}", "claimed_effective_at": "", "confidence": 0.6, "delta": { "basis_after": "unstated", "basis_before": "unstated", "basis_changed": false, "cfu_after": null, "cfu_before": null, "cfu_changed": false, "comparable": true, "organisms_added": [], "organisms_added_count": 0, "organisms_removed": [], "organisms_removed_count": 0, "pack_after": "120 Vegetarian Capsule(s)", "pack_before": "120 Vegetarian Capsule(s)" }, "edge_type": "observed_before", "entity_changes": {}, "from_label_version_id": "80084", "interval_censored": "1", "relationship_type": "derived_from_observation_windows", "source_observed_at": "2021-09-24", "to_label_version_id": "255435", "window_end": "", "window_start": "2017-10-21" }, { "changed_fields_json": "{}", "claimed_effective_at": "", "confidence": 0.6, "delta": { "basis_after": "unstated", "basis_before": "unstated", "basis_changed": false, "cfu_after": null, "cfu_before": null, "cfu_changed": false, "comparable": true, "organisms_added": [], "organisms_added_count": 0, "organisms_removed": [], "organisms_removed_count": 0, "pack_after": "120 Vegetarian Capsule(s)", "pack_before": "120 Vegetarian Capsule(s)" }, "edge_type": "possible_successor", "entity_changes": {}, "from_label_version_id": "80084", "interval_censored": "1", "relationship_type": "brand_name_organism_overlap", "source_observed_at": "2021-09-24", "to_label_version_id": "255435", "window_end": "2021-09-24", "window_start": "2017-10-21" } ], "weights": { "A1": 0.45, "A2": 0.55 } }