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  "affiliate_slug": "invivo",
  "also_sold_as": [],
  "alternatives": [
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      "gis": 72.775,
      "name": "Invivo Bio.Me Barrier",
      "price": null,
      "route": "/p/bio-me-barrier/",
      "shared_strain": "W23"
    },
    {
      "gis": 65.9,
      "name": "North American Herb & Spice Health-Bac",
      "price": null,
      "route": "/p/health-bac/",
      "shared_strain": "W51"
    },
    {
      "gis": 65.9,
      "name": "Physician's Strength Potent-Bac",
      "price": null,
      "route": "/p/potent-bac/",
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    }
  ],
  "brand_id": "brand:invivo",
  "brand_page": {
    "name": "Invivo",
    "route": "/b/invivo/"
  },
  "claims": [
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      "checked_at": "2026-09-20T00:00:00Z",
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      "denominator_status": "ok",
      "denominator_unit": "observed organisms",
      "entity_id": "sku:bio-me-oral",
      "number": 9,
      "page_id": "p--bio-me-oral",
      "provenance": "organism_rows.csv",
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      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.organisms",
      "query_links": [],
      "rows_after_dedupe": 9,
      "rows_before_dedupe": 9,
      "rule_id": "product.organisms",
      "sentence": "Invivo Bio.Me Oral: 9 of 9 observed organisms name a strain, and 0 print a deposit identifier. Latest observed label 217500. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.organisms",
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      "window": "NIH DSLD snapshot Sep 2026"
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      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--bio-me-oral:product.potency",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "observed label snapshots",
      "entity_id": "sku:bio-me-oral",
      "number": 0,
      "page_id": "p--bio-me-oral",
      "provenance": "organism_rows.csv; label_versions.csv",
      "query": "product label snapshots with explicit through_expiry or at_manufacture basis",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.potency",
      "query_links": [],
      "rows_after_dedupe": 0,
      "rows_before_dedupe": 1,
      "rule_id": "product.potency",
      "sentence": "Invivo Bio.Me Oral: 0 of 1 observed label snapshots state a potency basis; latest basis is not stated. Quantities reflect printed organism rows. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.potency",
      "values_json": "{\"basis\": \"not stated\", \"denominator\": 1, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Invivo Bio.Me Oral\", \"number\": 0, \"quantity_note\": \"Quantities reflect printed organism rows.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--bio-me-oral:product.gis",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "selected label snapshots",
      "entity_id": "sku:bio-me-oral",
      "number": 1,
      "page_id": "p--bio-me-oral",
      "provenance": "composite.csv; cohort_manifest.json",
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      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.gis",
      "query_links": [],
      "rows_after_dedupe": 1,
      "rows_before_dedupe": 1,
      "rule_id": "product.gis",
      "sentence": "Invivo Bio.Me Oral: 1 of 1 selected label snapshots have a numeric Gut Index Score; GIS 48.33 on the 100-point scale; rank class 4 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity. Window: NIH DSLD snapshot Sep 2026.",
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      "status": "ok",
      "template_id": "product.gis",
      "values_json": "{\"denominator\": 1, \"gis\": \"48.33\", \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Invivo Bio.Me Oral\", \"number\": 1, \"rank_note\": \"rank class 4 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity\", \"scale\": 100.0, \"share\": \"100.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--bio-me-oral:product.versions",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "formulation groups",
      "entity_id": "sku:bio-me-oral",
      "number": 1,
      "page_id": "p--bio-me-oral",
      "provenance": "label_versions.csv; label_version_edges.csv",
      "query": "observed label versions and distinct formulation IDs; latest typed edge by source_observed_at",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.versions",
      "query_links": [],
      "rows_after_dedupe": 1,
      "rows_before_dedupe": 1,
      "rule_id": "product.versions",
      "sentence": "Invivo Bio.Me Oral has 1 observed versions across 1 formulation groups; last recorded edge type: same product. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.versions",
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      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--bio-me-oral:product.price",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "observed label versions",
      "entity_id": "sku:bio-me-oral",
      "number": 0,
      "page_id": "p--bio-me-oral",
      "provenance": "prices.csv",
      "query": "numeric price observations joined by latest label_version_id; retain undefined reason",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.price",
      "query_links": [],
      "rows_after_dedupe": 0,
      "rows_before_dedupe": 1,
      "rule_id": "product.price",
      "sentence": "Invivo Bio.Me Oral: 0 of 1 observed versions have numeric prices; latest price No numeric price observation is available in this release.. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.price",
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      "window": "NIH DSLD snapshot Sep 2026"
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  "cohort_wave": "2026-09-20-w2",
  "compared_with": [],
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    "A1_components_json": "{\"identity\":0.7,\"quantity_disclosure\":0.0,\"potency_basis\":0.0,\"version_traceability\":1.0}",
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    "cohort_manifest_sha256": "3a8805d95e34cbd3ccdc36613e5bbcd4a75c17b7e07e420b65aa54f786a13400",
    "components_scored": "A1,A2",
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    "evidence_score_basis": "Existing GIS formula applied to known matching records as a lower bound; evidence_status records incomplete query coverage. Unknown evidence counts remain null.",
    "evidence_status": "ok",
    "formula_version": "gis_v1",
    "formulation_id": "formulation:217500",
    "geometric_sensitivity_interval": "[39.59307667376159,43.22533528785863]",
    "gis": 48.330555555555556,
    "gis_geo": 47.65064846636547,
    "identity_kind": "unique_commercial_code",
    "label_version_id": "217500",
    "mapping_tier": "T3",
    "p_top_quartile": 0,
    "pairwise_order_stability": 0.8460467663209275,
    "potency_basis": "unstated",
    "preference_sensitivity_interval": "[39.92380921061671,49.213439874017624]",
    "quantity_disclosure": 0,
    "rank_class": 4,
    "rank_median": 2879,
    "rank_p5": 2850,
    "rank_p95": 3076,
    "rank_uncertainty_interval": "[2850.0,3076.0]",
    "reason_codes_json": "[\"dose_unknown\"]",
    "score_status": "scored",
    "show_exact_rank": false,
    "sku_id": "sku:bio-me-oral"
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    "active_gut_ingredients": 0,
    "eligible": true,
    "excluded_name_match": false,
    "label_id": "217500",
    "organism_rows": 9,
    "source_kind": "detailed"
  },
  "entity_doses": {},
  "entity_id": "sku:bio-me-oral",
  "entity_pages": [
    {
      "entity_id": "species:bifidobacterium-bifidum",
      "name": "Bifidobacterium bifidum",
      "route": "/s/bifidobacterium-bifidum/"
    },
    {
      "entity_id": "strain:bifidobacterium-bifidum-w23",
      "name": "Bifidobacterium bifidum W23",
      "route": "/s/bifidobacterium-bifidum-w23/"
    },
    {
      "entity_id": "species:bifidobacterium-breve",
      "name": "Bifidobacterium breve",
      "route": "/s/bifidobacterium-breve/"
    },
    {
      "entity_id": "species:bifidobacterium-lactis",
      "name": "Bifidobacterium lactis",
      "route": "/s/bifidobacterium-lactis/"
    },
    {
      "entity_id": "strain:bifidobacterium-lactis-w51",
      "name": "Bifidobacterium lactis W51",
      "route": "/s/bifidobacterium-lactis-w51/"
    },
    {
      "entity_id": "species:enterococcus-faecium",
      "name": "Enterococcus faecium",
      "route": "/s/enterococcus-faecium/"
    },
    {
      "entity_id": "strain:enterococcus-faecium-w54",
      "name": "Enterococcus faecium W54",
      "route": "/s/enterococcus-faecium-w54/"
    },
    {
      "entity_id": "species:lacticaseibacillus-rhamnosus",
      "name": "Lacticaseibacillus rhamnosus",
      "route": "/s/lacticaseibacillus-rhamnosus/"
    },
    {
      "entity_id": "strain:lacticaseibacillus-rhamnosus-w71",
      "name": "Lacticaseibacillus rhamnosus W71",
      "route": "/s/lacticaseibacillus-rhamnosus-w71/"
    },
    {
      "entity_id": "species:lactiplantibacillus-plantarum",
      "name": "Lactiplantibacillus plantarum",
      "route": "/s/lactiplantibacillus-plantarum/"
    },
    {
      "entity_id": "strain:lactiplantibacillus-plantarum-w21",
      "name": "Lactiplantibacillus plantarum W21",
      "route": "/s/lactiplantibacillus-plantarum-w21/"
    },
    {
      "entity_id": "species:ligilactobacillus-salivarius",
      "name": "Ligilactobacillus salivarius",
      "route": "/s/ligilactobacillus-salivarius/"
    },
    {
      "entity_id": "strain:ligilactobacillus-salivarius-w24",
      "name": "Ligilactobacillus salivarius W24",
      "route": "/s/ligilactobacillus-salivarius-w24/"
    },
    {
      "entity_id": "species:streptococcus-thermophilus",
      "name": "Streptococcus thermophilus",
      "route": "/s/streptococcus-thermophilus/"
    }
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  "evidence": {
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    "above_studied_range": "0",
    "coverage_definition": "strain_count",
    "coverage_high": 1,
    "coverage_low": 0,
    "coverage_value": 0.5555555555555556,
    "dose_unknown": "1",
    "evidence_amount": 1,
    "evidence_entity_ids_json": "[\"strain:bifidobacterium-bifidum-w23\", \"strain:bifidobacterium-breve-w25\", \"strain:bifidobacterium-lactis-w51\", \"strain:enterococcus-faecium-w54\", \"strain:lacticaseibacillus-rhamnosus-w71\", \"strain:lactiplantibacillus-plantarum-w21\", \"strain:ligilactobacillus-salivarius-w24\", \"strain:ligilactobacillus-salivarius-w57\", \"strain:streptococcus-thermophilus-w69\"]",
    "evidence_queries_json": "[{\"entity_id\": \"strain:bifidobacterium-bifidum-w23\", \"query\": \"(((\\\"B. bifidum\\\"[tiab] OR \\\"Bifidobacterium bifidum\\\"[tiab]) AND (\\\"W23\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:bifidobacterium-breve-w25\", \"query\": \"(((\\\"B. breve\\\"[tiab] OR \\\"Bifidobacterium breve\\\"[tiab]) AND (\\\"W25\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:bifidobacterium-lactis-w51\", \"query\": \"(((\\\"B. animalis subsp. lactis\\\"[tiab] OR \\\"B. lactis\\\"[tiab] OR \\\"Bifidobacterium animalis subsp. lactis\\\"[tiab] OR \\\"Bifidobacterium lactis\\\"[tiab]) AND (\\\"W51\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:enterococcus-faecium-w54\", \"query\": \"(((\\\"E. faecium\\\"[tiab] OR \\\"Enterococcus faecium\\\"[tiab]) AND (\\\"W54\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:lacticaseibacillus-rhamnosus-w71\", \"query\": \"(((\\\"L. rhamnosus\\\"[tiab] OR \\\"Lacticaseibacillus rhamnosus\\\"[tiab] OR \\\"Lactobacillus rhamnosus\\\"[tiab]) AND (\\\"W71\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:lactiplantibacillus-plantarum-w21\", \"query\": \"(((\\\"L. plantarum\\\"[tiab] OR \\\"Lactiplantibacillus plantarum\\\"[tiab] OR \\\"Lactobacillus plantarum\\\"[tiab]) AND (\\\"W21\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:ligilactobacillus-salivarius-w24\", \"query\": \"(((\\\"L. salivarius\\\"[tiab] OR \\\"Lactobacillus salivarius\\\"[tiab] OR \\\"Ligilactobacillus salivarius\\\"[tiab]) AND (\\\"W24\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:ligilactobacillus-salivarius-w57\", \"query\": \"(((\\\"L. salivarius\\\"[tiab] OR \\\"Lactobacillus salivarius\\\"[tiab] OR \\\"Ligilactobacillus salivarius\\\"[tiab]) AND (\\\"W57\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}, {\"entity_id\": \"strain:streptococcus-thermophilus-w69\", \"query\": \"(((\\\"S. thermophilus\\\"[tiab] OR \\\"Streptococcus thermophilus\\\"[tiab]) AND (\\\"W69\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}]",
    "evidence_sources_json": "{\"strain:bifidobacterium-bifidum-w23\": \"v2\", \"strain:bifidobacterium-breve-w25\": \"v2\", \"strain:bifidobacterium-lactis-w51\": \"v2\", \"strain:enterococcus-faecium-w54\": \"v2\", \"strain:lacticaseibacillus-rhamnosus-w71\": \"v2\", \"strain:lactiplantibacillus-plantarum-w21\": \"v2\", \"strain:ligilactobacillus-salivarius-w24\": \"v2\", \"strain:ligilactobacillus-salivarius-w57\": \"v2\", \"strain:streptococcus-thermophilus-w69\": \"v2\"}",
    "known_records_count": 23,
    "label_version_id": "217500",
    "match_state": "strain_only",
    "n_rct_human": 23,
    "observed_positive_trial_dose_match": "",
    "query_dates": "2026-09-15",
    "rct_count": 23,
    "state": "strain_only",
    "status": "ok",
    "unallocated_share": 1,
    "unmatchable_reason": "dose_unknown"
  },
  "formula_version": "gis_v1",
  "generated_at": "2026-09-20T00:00:00Z",
  "label_facts": {
    "cfu_per_day": null,
    "days_blocker": "",
    "days_of_supply": 15,
    "form": "Powder",
    "net": {
      "display": "30 Gram(s)",
      "quantity": 30,
      "unit": "Gram(s)"
    },
    "other_ingredient_count": 3,
    "other_ingredients": [
      "Maize Starch",
      "Maltodextrin",
      "hydrolyzed Rice Protein"
    ],
    "price_per_day": null,
    "printed_claim_count": 1,
    "printed_claims": [
      "All Other"
    ],
    "product_type": "Non-Nutrient/Non-Botanical",
    "serving": {
      "per_day": 2,
      "size": 1,
      "unit": "Gram(s)"
    },
    "suggested_use": "Directions:\nMix 1g (0.5 tsp) twice daily into 50ml of water. Leave for 1 minute. Stir before swilling in your mouth for 20 seconds before swallowing.",
    "target_groups": [
      "Vegetarian",
      "Adult (18 - 50 Years)"
    ],
    "units_comparable": true,
    "units_converted": false,
    "upc": "7 105353 660130 >"
  },
  "label_versions": [
    {
      "brand": "Invivo",
      "censored": "1",
      "diff_flags_json": "{}",
      "effective_from": "",
      "effective_to": "",
      "entry_date": "2020-04-23",
      "label_version_id": "217500",
      "link_confidence": "",
      "observation_kind": "detailed",
      "observed": "1",
      "observed_at": "2020-04-23",
      "off_market_date": "",
      "prev_version_id": "",
      "product": "Bio.Me Oral",
      "record_key": "bbdfad5c7f04da0dcc469f6b2f63b3547d63d2f18659e99a05bdcdab5c18bf8c",
      "relationships_json": "[{\"type\":\"Package size difference, same product\",\"labelId\":215260},{\"type\":\"Package size difference, same product\",\"labelId\":259865}]",
      "sku_id": "sku:bio-me-oral",
      "upc": "7 105353 660130 >"
    }
  ],
  "latest_label_id": "217500",
  "name": "Invivo Bio.Me Oral",
  "opinion_type": "observed",
  "organisms": [
    {
      "blend_total_cfu": "2500000000",
      "brand": "Invivo",
      "canonical_entity_id": "strain:bifidobacterium-bifidum-w23",
      "cfu_basis": "unstated",
      "cfu_basis_row_ref": "",
      "cfu_per_serving": "",
      "cfu_scope": "none",
      "cfu_source": "none",
      "confidence": "0.85",
      "culture_collection_id": "",
      "designation_type": "commercial_code",
      "enumeration_method": "unstated",
      "extracted_from": "ingredientRows[0].nestedRows[0]",
      "genus_norm": "Bifidobacterium",
      "genus_raw": "Bifidobacterium",
      "in_proprietary_blend": "1",
      "label_id": "217500",
      "mapping_tier": "T3",
      "match_confidence": "0.85",
      "observation_kind": "detailed",
      "observed_at": "2020-04-23",
      "opinion_type": "observed",
      "parser_version": "w0-v1.1",
      "product": "Bio.Me Oral",
      "quantity_unit": "",
      "quantity_value": null,
      "raw_name": "Bifidobacterium bifidum W23",
      "reason_code": "",
      "record_key": "fa5cc8f3d45707b91e3a00e4d2a4d3cb7ad8fddda007cb7470593d7df9a494d5",
      "retrieved_at": "2026-09-06T13:52:01Z",
      "source_content_hash": "e3409ef36d167fe805d2978a6651bf7c78ba08795afbdc65a6dd0e7e8f7cf9a9",
      "source_id": "NIH_DSLD:217500",
      "source_record_id": "217500",
      "source_url": "https://dsld.od.nih.gov/label/217500",
      "species": "bifidum",
      "status": "scored",
      "strain_designation": "W23",
      "taxon_recognized": "1",
      "viability_state": "unstated"
    },
    {
      "blend_total_cfu": "2500000000",
      "brand": "Invivo",
      "canonical_entity_id": "strain:bifidobacterium-breve-w25",
      "cfu_basis": "unstated",
      "cfu_basis_row_ref": "",
      "cfu_per_serving": "",
      "cfu_scope": "none",
      "cfu_source": "none",
      "confidence": "0.85",
      "culture_collection_id": "",
      "designation_type": "commercial_code",
      "enumeration_method": "unstated",
      "extracted_from": "ingredientRows[0].nestedRows[1]",
      "genus_norm": "Bifidobacterium",
      "genus_raw": "Bifidobacterium",
      "in_proprietary_blend": "1",
      "label_id": "217500",
      "mapping_tier": "T3",
      "match_confidence": "0.85",
      "observation_kind": "detailed",
      "observed_at": "2020-04-23",
      "opinion_type": "observed",
      "parser_version": "w0-v1.1",
      "product": "Bio.Me Oral",
      "quantity_unit": "",
      "quantity_value": null,
      "raw_name": "Bifidobacterium breve W25",
      "reason_code": "",
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