{
  "affiliate_slug": "bio-nutrition",
  "also_sold_as": [],
  "alternatives": [],
  "brand_id": "brand:bio-nutrition",
  "brand_page": null,
  "claims": [
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--total-colon-wellness:product.organisms",
      "denominator": 2,
      "denominator_status": "ok",
      "denominator_unit": "observed organisms",
      "entity_id": "sku:total-colon-wellness",
      "number": 0,
      "page_id": "p--total-colon-wellness",
      "provenance": "organism_rows.csv",
      "query": "latest observed label organism rows; designation and deposit must be printed",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.organisms",
      "query_links": [],
      "rows_after_dedupe": 0,
      "rows_before_dedupe": 2,
      "rule_id": "product.organisms",
      "sentence": "Bio Nutrition Total Colon Wellness: 0 of 2 observed organisms name a strain, and 0 print a deposit identifier. Latest observed label 200645. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.organisms",
      "values_json": "{\"denominator\": 2, \"deposits\": 0, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Bio Nutrition Total Colon Wellness\", \"number\": 0, \"observation_note\": \"Latest observed label 200645.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--total-colon-wellness:product.potency",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "observed label snapshots",
      "entity_id": "sku:total-colon-wellness",
      "number": 0,
      "page_id": "p--total-colon-wellness",
      "provenance": "organism_rows.csv; label_versions.csv",
      "query": "product label snapshots with explicit through_expiry or at_manufacture basis",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.potency",
      "query_links": [],
      "rows_after_dedupe": 0,
      "rows_before_dedupe": 1,
      "rule_id": "product.potency",
      "sentence": "Bio Nutrition Total Colon Wellness: 0 of 1 observed label snapshots state a potency basis; latest basis is not stated. Quantities reflect printed organism rows. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.potency",
      "values_json": "{\"basis\": \"not stated\", \"denominator\": 1, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Bio Nutrition Total Colon Wellness\", \"number\": 0, \"quantity_note\": \"Quantities reflect printed organism rows.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--total-colon-wellness:product.gis",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "selected label snapshots",
      "entity_id": "sku:total-colon-wellness",
      "number": 1,
      "page_id": "p--total-colon-wellness",
      "provenance": "composite.csv; cohort_manifest.json",
      "query": "latest numeric composite availability, GIS, quartile rank_class and normative preference-weight perturbation; no invented rank interval",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.gis",
      "query_links": [],
      "rows_after_dedupe": 1,
      "rows_before_dedupe": 1,
      "rule_id": "product.gis",
      "sentence": "Bio Nutrition Total Colon Wellness: 1 of 1 selected label snapshots have a numeric Gut Index Score; GIS 61.75 on the 100-point scale; rank class 3 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.gis",
      "values_json": "{\"denominator\": 1, \"gis\": \"61.75\", \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Bio Nutrition Total Colon Wellness\", \"number\": 1, \"rank_note\": \"rank class 3 of 4 across 3,279 scored formulations; nominal weights varied from 80.0% to 120.0% in preference sensitivity\", \"scale\": 100.0, \"share\": \"100.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--total-colon-wellness:product.versions",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "formulation groups",
      "entity_id": "sku:total-colon-wellness",
      "number": 1,
      "page_id": "p--total-colon-wellness",
      "provenance": "label_versions.csv; label_version_edges.csv",
      "query": "observed label versions and distinct formulation IDs; latest typed edge by source_observed_at",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.versions",
      "query_links": [],
      "rows_after_dedupe": 1,
      "rows_before_dedupe": 1,
      "rule_id": "product.versions",
      "sentence": "Bio Nutrition Total Colon Wellness has 1 observed versions across 1 formulation groups; last recorded edge type: no typed edge. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.versions",
      "values_json": "{\"denominator\": 1, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"last_change\": \"no typed edge\", \"name\": \"Bio Nutrition Total Colon Wellness\", \"number\": 1, \"share\": \"100.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    },
    {
      "checked_at": "2026-09-20T00:00:00Z",
      "claim_id": "claim:p--total-colon-wellness:product.price",
      "denominator": 1,
      "denominator_status": "ok",
      "denominator_unit": "observed label versions",
      "entity_id": "sku:total-colon-wellness",
      "number": 0,
      "page_id": "p--total-colon-wellness",
      "provenance": "prices.csv",
      "query": "numeric price observations joined by latest label_version_id; retain undefined reason",
      "query_commit": "90a5050d2327baae3d738638237b48fb29cb01b0",
      "query_id": "product.price",
      "query_links": [],
      "rows_after_dedupe": 0,
      "rows_before_dedupe": 1,
      "rule_id": "product.price",
      "sentence": "Bio Nutrition Total Colon Wellness: 0 of 1 observed versions have numeric prices; latest price No numeric price observation is available in this release.. Window: NIH DSLD snapshot Sep 2026.",
      "snapshot_hash": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
      "status": "ok",
      "template_id": "product.price",
      "values_json": "{\"denominator\": 1, \"labels\": \"labels in the NIH DSLD snapshot (Sep 2026)\", \"name\": \"Bio Nutrition Total Colon Wellness\", \"number\": 0, \"price_text\": \"No numeric price observation is available in this release.\", \"share\": \"0.0%\", \"window\": \"NIH DSLD snapshot Sep 2026\"}",
      "window": "NIH DSLD snapshot Sep 2026"
    }
  ],
  "cohort_manifest_sha256": "3a8805d95e34cbd3ccdc36613e5bbcd4a75c17b7e07e420b65aa54f786a13400",
  "cohort_wave": "2026-09-20-w2",
  "compared_with": [],
  "composite": {
    "A1": 15,
    "A1_components_json": "{\"identity\":0.0,\"quantity_disclosure\":0.0,\"potency_basis\":0.0,\"version_traceability\":1.0}",
    "A2": 100,
    "cohort_manifest_sha256": "3a8805d95e34cbd3ccdc36613e5bbcd4a75c17b7e07e420b65aa54f786a13400",
    "components_scored": "A1,A2",
    "effective_weight_json": "{\"A1\":0.2496227130555789,\"A2\":0.640418048760888}",
    "evidence_score_basis": "Existing GIS formula applied to known matching records as a lower bound; evidence_status records incomplete query coverage. Unknown evidence counts remain null.",
    "evidence_status": "ok",
    "formula_version": "gis_v1",
    "formulation_id": "formulation:200645",
    "geometric_sensitivity_interval": "[0.0,0.0]",
    "gis": 61.75000000000001,
    "gis_geo": 42.58347183047368,
    "identity_kind": "species_or_t4",
    "label_version_id": "200645",
    "mapping_tier": "T4",
    "p_top_quartile": 0,
    "pairwise_order_stability": 0.8460467663209275,
    "potency_basis": "unstated",
    "preference_sensitivity_interval": "[0.0,66.42409345068155]",
    "quantity_disclosure": 0,
    "rank_class": 3,
    "rank_median": 1976,
    "rank_p5": 1798,
    "rank_p95": 2389.0499999999993,
    "rank_uncertainty_interval": "[1798.0,2389.0499999999993]",
    "reason_codes_json": "[\"dose_unknown\",\"identity_t4\"]",
    "score_status": "scored",
    "show_exact_rank": false,
    "sku_id": "sku:total-colon-wellness"
  },
  "eligibility": {
    "active_gut_ingredients": 1,
    "eligible": true,
    "excluded_name_match": false,
    "label_id": "200645",
    "organism_rows": 2,
    "source_kind": "detailed"
  },
  "entity_doses": {},
  "entity_id": "sku:total-colon-wellness",
  "entity_pages": [
    {
      "entity_id": "species:lactobacillus-acidophilus",
      "name": "Lactobacillus acidophilus",
      "route": "/s/lactobacillus-acidophilus/"
    },
    {
      "entity_id": "gut_substance:slippery-elm",
      "name": "slippery elm",
      "route": "/s/slippery-elm/"
    }
  ],
  "evidence": {
    "A2": 100,
    "above_studied_range": "0",
    "coverage_definition": "strain_count",
    "coverage_high": 1,
    "coverage_low": 0,
    "coverage_value": 1,
    "dose_unknown": "1",
    "evidence_amount": 1,
    "evidence_entity_ids_json": "[\"species:lactobacillus-acidophilus\"]",
    "evidence_queries_json": "[{\"entity_id\": \"species:lactobacillus-acidophilus\", \"query\": \"(((\\\"Lactobacillus acidophilus\\\"[tiab]))) AND randomized controlled trial[pt] AND humans[mh] NOT (retracted publication[pt] OR retraction of publication[pt])\", \"as_of\": \"2026-09-15\"}]",
    "evidence_sources_json": "{\"species:lactobacillus-acidophilus\": \"v2\"}",
    "known_records_count": 381,
    "label_version_id": "200645",
    "match_state": "strain_only",
    "n_rct_human": 381,
    "observed_positive_trial_dose_match": "",
    "query_dates": "2026-09-15",
    "rct_count": 381,
    "state": "strain_only",
    "status": "ok",
    "unallocated_share": 1,
    "unmatchable_reason": "dose_unknown"
  },
  "formula_version": "gis_v1",
  "generated_at": "2026-09-20T00:00:00Z",
  "label_facts": {
    "cfu_per_day": null,
    "days_blocker": "",
    "days_of_supply": 10,
    "form": "Tablet or Pill",
    "net": {
      "display": "60 Tablet(s)",
      "quantity": 60,
      "unit": "Tablet(s)"
    },
    "other_ingredient_count": 5,
    "other_ingredients": [
      "Di Calcium Phosphate",
      "Cellulose",
      "Silica",
      "Vegetable Stearate",
      "Pharmaceutical Glaze"
    ],
    "price_per_day": null,
    "printed_claim_count": 2,
    "printed_claims": [
      "All Other",
      "Structure/Function"
    ],
    "product_type": "Other Combinations",
    "serving": {
      "per_day": 3,
      "size": 2,
      "unit": "Tablet(s)"
    },
    "suggested_use": "Suggested Use: For daily cleansing take one (1) or two (2) tablets after evening meal or before bed. For short term intensive cleansing take one (1) or two (2) tablets three (3) times daily after meals or as recommended by a health care professional.",
    "target_groups": [
      "Vegetarian",
      "Adult (18 - 50 Years)",
      "Dairy Free",
      "Sugar Free"
    ],
    "units_comparable": true,
    "units_converted": false,
    "upc": "8 54936 00307 5"
  },
  "label_versions": [
    {
      "brand": "Bio Nutrition",
      "censored": "1",
      "diff_flags_json": "{}",
      "effective_from": "",
      "effective_to": "",
      "entry_date": "2019-04-25",
      "label_version_id": "200645",
      "link_confidence": "",
      "observation_kind": "detailed",
      "observed": "1",
      "observed_at": "2019-04-25",
      "off_market_date": "",
      "prev_version_id": "",
      "product": "Total Colon Wellness",
      "record_key": "577b59407adbaebefda12a656520557461d6d3e75aa122602fc5a749e21383d1",
      "relationships_json": "[]",
      "sku_id": "sku:total-colon-wellness",
      "upc": "8 54936 00307 5"
    }
  ],
  "latest_label_id": "200645",
  "name": "Bio Nutrition Total Colon Wellness",
  "opinion_type": "observed",
  "organisms": [
    {
      "blend_total_cfu": "",
      "brand": "Bio Nutrition",
      "canonical_entity_id": "species:lactobacillus-acidophilus",
      "cfu_basis": "unstated",
      "cfu_basis_row_ref": "",
      "cfu_per_serving": "",
      "cfu_scope": "none",
      "cfu_source": "none",
      "confidence": "0.60",
      "culture_collection_id": "",
      "designation_type": "none",
      "enumeration_method": "unstated",
      "extracted_from": "ingredientRows[17].nestedRows[0]",
      "genus_norm": "Lactobacillus",
      "genus_raw": "Lactobacillus",
      "in_proprietary_blend": "1",
      "label_id": "200645",
      "mapping_tier": "T4",
      "match_confidence": "0.60",
      "observation_kind": "detailed",
      "observed_at": "2019-04-25",
      "opinion_type": "observed",
      "parser_version": "w0-v1.1",
      "product": "Total Colon Wellness",
      "quantity_unit": "",
      "quantity_value": null,
      "raw_name": "Lactobacillus acidophilus",
      "reason_code": "",
      "record_key": "da6cd7ff2f779cd59c0cf48b933e5345224a0a0dd11869d26fb79cedb53eacdd",
      "retrieved_at": "2026-09-06T15:24:01Z",
      "source_content_hash": "e9c792ef9a04eff36b797c37570b95e87ad61aaf690daf9158c3a95d3eff3815",
      "source_id": "NIH_DSLD:200645",
      "source_record_id": "200645",
      "source_url": "https://dsld.od.nih.gov/label/200645",
      "species": "acidophilus",
      "status": "scored",
      "strain_designation": "",
      "taxon_recognized": "1",
      "viability_state": "unstated"
    },
    {
      "blend_total_cfu": "",
      "brand": "Bio Nutrition",
      "canonical_entity_id": "",
      "cfu_basis": "unstated",
      "cfu_basis_row_ref": "",
      "cfu_per_serving": "",
      "cfu_scope": "none",
      "cfu_source": "none",
      "confidence": "0.20",
      "culture_collection_id": "",
      "designation_type": "none",
      "enumeration_method": "unstated",
      "extracted_from": "ingredientRows[17].nestedRows[1]",
      "genus_norm": "",
      "genus_raw": "",
      "in_proprietary_blend": "1",
      "label_id": "200645",
      "mapping_tier": "T4",
      "match_confidence": "0.20",
      "observation_kind": "detailed",
      "observed_at": "2019-04-25",
      "opinion_type": "observed",
      "parser_version": "w0-v1.1",
      "product": "Total Colon Wellness",
      "quantity_unit": "",
      "quantity_value": null,
      "raw_name": "Bifidus regularis",
      "reason_code": "identity_not_resolved",
      "record_key": "6732521dfc703e8a9936e0df9ba022dd0239f4e90ccade2503e40d12005b1afb",
      "retrieved_at": "2026-09-06T15:24:01Z",
      "source_content_hash": "e9c792ef9a04eff36b797c37570b95e87ad61aaf690daf9158c3a95d3eff3815",
      "source_id": "NIH_DSLD:200645",
      "source_record_id": "200645",
      "source_url": "https://dsld.od.nih.gov/label/200645",
      "species": "",
      "status": "unmatchable",
      "strain_designation": "",
      "taxon_recognized": "0",
      "viability_state": "unstated"
    }
  ],
  "page_id": "p--total-colon-wellness",
  "page_type": "product",
  "panels": [],
  "price": null,
  "printed_quantity": {
    "basis": "unstated",
    "blend_rows": 2,
    "rows": 2,
    "rows_with_quantity": 0,
    "total_cfu": null,
    "total_cfu_printed": null,
    "total_cfu_unreadable": false
  },
  "qualification": "observed",
  "quantity_note": "Quantities reflect printed organism rows.",
  "related_reports": [
    {
      "name": "Potency basis census",
      "route": "/reports/potency-basis-census/"
    },
    {
      "name": "Strain dose match",
      "route": "/reports/strain-dose-match/"
    },
    {
      "name": "Supplier code network",
      "route": "/reports/supplier-code-network/"
    }
  ],
  "related_tools": [
    {
      "name": "Unit value calculator",
      "route": "/calc/"
    },
    {
      "name": "DSLD product check",
      "route": "/check/"
    }
  ],
  "release": "2026-09-20",
  "route": "/p/total-colon-wellness/",
  "score_context": {
    "percentile": 39.4,
    "scored_formulations": 4101
  },
  "score_scale": 100,
  "source_sha256": "b7633f732437b71d37c215a03b19abfa8c91d45411579d976d6a926a0140339a",
  "strain_evidence": [
    {
      "entity_id": "species:lactobacillus-acidophilus",
      "evidence_status": "ok",
      "name": "Lactobacillus acidophilus",
      "query_valid": true,
      "rct_count": 381,
      "route": "/s/lactobacillus-acidophilus/"
    },
    {
      "entity_id": "gut_substance:slippery-elm",
      "evidence_status": "ok",
      "name": "slippery elm",
      "query_valid": true,
      "rct_count": 1,
      "route": "/s/slippery-elm/"
    }
  ],
  "version_edges": [],
  "weights": {
    "A1": 0.45,
    "A2": 0.55
  }
}
