Axis 2
Studiedness
- Evidence amount
- 1.00
- Direction balance
- The direction of the study results has not been extracted.
- PMID records loaded
- 17
- Records after title/year deduplication
- 17
entity · release 2026-09-20
Streptococcus salivarius K12
Structured fields rendered from the release dataset. Unknown values retain a reason; price is outside GIS.
Across the corpus
How this organism is actually sold
- Printed CFU per serving
- 575,000,000 – 2,000,000,000; median 1,000,000,000. Measured on the 5 of 7 published products carrying it whose latest published label prints a figure for it; the rest print a blend total or no quantity, and earlier label versions in the table below may print other figures. 0 row(s) print a CFU below 1 000 and are excluded as a label or parsing artefact.
- Forms
- Lozenge: 4 · Tablet or Pill: 3 · counted across the 7 of 7 published products whose label states a form
- Brands carrying it
- childlife-essentials (1) · naturesplus (1) · naturesplus-animal-parade (1) · now (1) · renew-life (1) · the five largest of 7 brands with a published product
- Published product pages
- 7
Products
Published products carrying this organism
| Product | Printed CFU | Printed dose | Cost per day | Form | Gut Index Score |
|---|---|---|---|---|---|
| NOW OralBiotic | 1,000,000,000 | not printed | not observed | Lozenge | 88.53 |
| Life Extension Advanced Oral Hygiene | 575,000,000 | not printed | not observed | Lozenge | 88.53 |
| Protocol For Life Balance E.N.T. Biotic | 1,000,000,000 | not printed | not observed | Lozenge | 88.53 |
| NaturesPlus Adult's Ear, Nose & Throat Lozenges Tropical Cherry-Berry | 2,000,000,000 | not printed | not observed | Lozenge | 84.25 |
| NaturesPlus Animal Parade Inner Ear Cherry Flavor | 1,000,000,000 | not printed | not observed | Tablet or Pill | 77.50 |
| Renew Life Kids Probiotic Ear, Nose & Throat Orange Burst Flavor | not printed | not printed | not observed | Tablet or Pill | 73.00 |
| ChildLife Essentials LiveBiotics Oral Care Natural Strawberry Flavor | not printed | not printed | not observed | Tablet or Pill | 45.28 |
Containing labels15
Evidence amount1.00
Direction balanceThe direction of the study results has not been extracted.
Matched PubMed records
17 records (retracted records excluded; 0 retracted records match the query separately). PubMed query
Matched records include trials of multi-ingredient products; this is not a count of trials of this entity alone.
- 2026 · Preventing otitis media and respiratory tract infections with the oral probiotic Streptococcus salivarius K12.
- 2026 · Tongue brushing and oral probiotics for the treatment of halitosis: a randomized controlled trial.
- 2025 · Effect of probiotic lozenges on improvement in tympanometric classification within 12 weeks in children aged 3-6 years with adenoid hypertrophy and otitis media with effusion undergoing non-surgical management: a randomized controlled trial.
- 2025 · Oral Probiotic Containing Streptococcus salivarius K12 and Lactobacillus brevis CD2 for Preventing Bacterial Pneumonia in Severe COVID-19: Randomized Clinical Trial.
- 2024 · Streptococcus salivarius K12 Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial.
- 2023 · Streptococcus salivarius Probiotics to Prevent Acute Otitis Media in Children: A Randomized Clinical Trial.
- 2023 · Use of Streptococcus salivarius K12 in supporting the mucosal immune function of active young subjects: A randomised double-blind study.
- 2022 · The Effect of Oral Probiotics (Streptococcus Salivarius k12) on the Salivary Level of Secretory Immunoglobulin A, Salivation Rate, and Oral Biofilm: A Pilot Randomized Clinical Trial.
- 2021 · Multi-Strain Probiotic Supplementation with a Product Containing Human-Native S. salivarius K12 in Healthy Adults Increases Oral S. salivarius.
- 2021 · Human Systemic Immune Response to Ingestion of the Oral Probiotic Streptococcus salivarius BLIS K12.
ClinicalTrials.gov
16 interventional studies. ClinicalTrials.gov query
This species has 6 tracked designations; this one appears on 15 labels (median 4.5).
Other printed names
- Streptococcus salivarius K-12
Species and related strains
Axis 1 · inverted
Containing label versions
Showing 15 of 15 rows, ordered by Gut Index Score descending, then DSLD label ID. Download full CSV · Download full JSON.
| Brand | Product | DSLD | Gut Index Score | Strain named | Per-organism quantity | Potency basis | Versions |
|---|---|---|---|---|---|---|---|
| NatureCity | TrueOC Quick Melt Orange Flavor | 320945 | 95.28 | true | 1,000,000,000 CFU | through expiry | 1 |
| Life Extension | Advanced Oral Hygiene | 59635 | 88.53 | true | 575,000,000 CFU | at manufacture | 1 |
| Protocol For Life Balance | E.N.T. Biotic | 73180 | 88.53 | true | 1,000,000,000 CFU | at manufacture | 1 |
| NOW | OralBiotic | 245611 | 88.53 | true | 1,000,000,000 CFU | at manufacture | 2 |
| NOW | OralBiotic | 313891 | 88.53 | true | 1,000,000,000 CFU | at manufacture | 2 |
| NaturesPlus | Adult's Ear, Nose & Throat Lozenges Tropical Cherry-Berry | 298653 | 84.25 | true | 2,000,000,000 CFU | through expiry | 1 |
| NaturesPlus Animal Parade | Inner Ear Cherry Flavor | 319154 | 77.50 | true | 1,000,000,000 CFU | at manufacture | 1 |
| Renew Life | Kids Probiotic Ear, Nose & Throat Orange Burst Flavor | 203507 | 73.00 | true | not printed for this organism | through expiry | 1 |
| Solaray | Mycrobiome Probiotic Mouth & Throat | 255424 | 66.25 | true | not printed for this organism | at manufacture | 2 |
| ChildLife Essentials | LiveBiotics Oral Care Natural Strawberry Flavor | 299255 | 45.28 | true | not printed for this organism | not stated | 1 |
| SimplyBiotix | Oral & Sinus Cinnamon Stick Flavor | 201971 | Not available in this release. | true | undefined: light snapshot | not stated | 1 |
| AOR Advanced Orthomolecular Research Advanced | Breath Biotics Wintermint Flavour with Blis K12 | 214440 | Not available in this release. | true | undefined: light snapshot | not stated | 1 |
| Nature's Trove | Oral Probiotic 20 mg Cherry Flavor | 229460 | Not available in this release. | true | undefined: light snapshot | not stated | 1 |
| Life Extension Florassist | Throat Health | 232097 | Not available in this release. | true | undefined: light snapshot | not stated | 1 |
| Swanson | Oral Probiotic Formula Natural Strawberry Flavor | 322740 | Not available in this release. | true | undefined: light snapshot | not stated | 1 |
Axis 3
Measurement integrity
Not a measurement product, so this axis does not apply.
Axis 4
Reddit mention panel
0 observed mentions; no aggregate panel matched this entity.
Elsewhere in this release
Related pages
Findings computed over the whole corpus: Strain naming census · Label designation changes · Strain dose match · Stability literature gaps
Tools: DSLD product check · Unit value calculator
Citation
Cite this page
Ivitskiy, I. (2026). Streptococcus salivarius K12. Gut Registry, release 2026-09-20. Elanvale Ltd. https://gutregistry.com/s/streptococcus-salivarius-k12/
The underlying tables are published under CC BY 4.0: this page as CSV · as JSON · full release and data dictionary. Cell-level provenance names the source record and its observation date.
Citable atoms
Release claims
Streptococcus salivarius K12 appears on 15 of 13,330 labels in the NIH DSLD snapshot (Sep 2026), from 14 brands; tied with 6 designations by distinct label count.
15 / 13330 observed label versions · NIH DSLD snapshot Sep 2026 · entity.prevalence · checked 2026-09-20T00:00:00Z · snapshot b7633f7324377 of 15 containing labels in the NIH DSLD snapshot (Sep 2026) print a quantity for Streptococcus salivarius K12 (46.7%); 5 light records have quantities unavailable.
7 / 15 containing labels · NIH DSLD snapshot Sep 2026 · entity.quantity · checked 2026-09-20T00:00:00Z · snapshot b7633f73243717 PubMed records indexed as human randomized controlled trials match the published query (as of 2026-09-15). 17 records (retracted records excluded; 0 retracted records match the query separately).
17 / 17 loaded PMID records · NIH DSLD snapshot Sep 2026 · entity.evidence · checked 2026-09-20T00:00:00Z · snapshot b7633f73243716 interventional studies on ClinicalTrials.gov match the published query.
Published ClinicalTrials.gov query
16 / Not available in this release. interventional registry studies · NIH DSLD snapshot Sep 2026 · entity.registered_trials · checked 2026-09-20T00:00:00Z · snapshot b7633f7324370 of 14 SKUs containing Streptococcus salivarius K12 have a numeric price observation (0.0%) in the release accompanying the NIH DSLD snapshot Sep 2026.
0 / 14 containing SKUs · NIH DSLD snapshot Sep 2026 · entity.price · checked 2026-09-20T00:00:00Z · snapshot b7633f732437